Peripheral neuropathy =E2=80=94 Managing the side = effects of chemotherapy

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Living with cancer blog
June 10, 2010

Peripheral neuropathy =E2=80=94 Managing the side effects of = chemotherapy

By Sheryl M. Ness

1 comment posted

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Many of you have written in through this blog and mentioned you're = dealing=20 with symptoms of peripheral neuropathy as a result of chemotherapy = treatment.=20

Peripheral neuropathy is caused by damage to nerves, most commonly = the=20 sensory nerves (nerves that sense touch, heat or pain). As chemotherapy = travels=20 throughout the body to target and kill cancer cells, it can also cause = damage to=20 the nerve cells.

Certain chemotherapy drugs are more often linked to peripheral = neuropathy;=20 these include the platinum-based drugs, taxanes, epothilones, and plant = alkaloid=20 drugs, as well as Thalidomide and Bortezomib. Symptoms of peripheral = neuropathy=20 can begin any time after treatment is started and can worsen as = treatment=20 continues.

The most common symptoms include:

Pain, burning or tingling in fingers, toes, hands and feet=20
Loss of sensation to touch=20
Difficulty picking things up or buttoning clothes=20
Weakness, cramping or pain in hands and/or feet=20
Sensitivity to temperature extremes=20
Muscle weakness and balance problems=20
Constipation=20
Decreased reflexes

You may be at higher risk for developing peripheral neuropathy if you = have=20 pre-existing conditions such as diabetes, alcoholism, malnutrition, = vitamin B=20 deficiencies, or have had previous chemotherapy, radiation or surgery. =

Symptoms may appear the to be the strongest just after your = chemotherapy=20 treatment, and can last until 3-5 months after treatment has been = completed.=20 Symptoms may lessen over time, but it's a gradual process that requires = several=20 months to resolve.

Unfortunately, in some cases, the damage is irreversible and may not = diminish=20 in intensity. It's important to report any symptoms of neuropathy to = your cancer=20 doctor during and after treatment. Discuss with your doctor the options = for rest=20 periods from chemotherapy, dose reduction or delays in treatment to = lesson your=20 symptoms.

Comfort measures that may help relieve symptoms include:

Splinting and protecting affected area=20
Massage, physical therapy, and acupuncture=20
Relaxation therapy=20
Use of vitamins, especially B vitamins (B-1, B-6, and B-12). Ask = your=20 health care provider about dosing. Vitamin E and niacin are also = important to=20 nerve health.=20
Gentle laxatives for constipation=20
Prescribed medication such as steroids, lidocaine patches, = capsaicin=20 creams, anti-depressants, anti-seizure medications, and pain = medications=20

Some practical tips to consider if you have symptoms of peripheral=20 neuropathy:

Protect your hands and feet where sensation is decreased (wear = good=20 footwear and protect from injury).=20
Be aware of temperature changes, such as extreme cold or hot = (check water=20 temperature of your shower and bath water, use gloves when doing = housework).=20
Always check for any cuts, abrasions, burns and injury to hands = and feet.=20
Don't drink alcohol; this may make symptoms worse over time.=20
Use handrails, canes and other assistive devices if needed for = balance.=20

Peripheral neuropathy symptoms are challenging to deal with and can = affect=20 your quality of life significantly. Ask your doctor or nurse for ideas = and=20 suggestions to help relieve symptoms. Use this blog to discuss your = strategies=20 for dealing with the problem of peripheral neuropathy.

1 comment posted

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Post=20 a comment

blog=20 index=20

See Also
Hand Scheduled
Section=20 Focus=20
Cancer=20 surgery: Physically removing cancer=20
Pod= cast:=20 Managing nausea and vomiting during chemotherapy=20
Podcast:=20 Deciding on chemotherapy=20
Po= dcast:=20 Managing fatigue during chemotherapy=20
Diarrhea:=20 Cancer-related causes and how to cope=20
Vid= eo:=20 PICC line placement=20
No = appetite? How=20 to get nutrition during cancer treatment=20
Cancer=20 pain: Relief is possible=20
Slide= =20 show: Radiation therapy treatment planning=20
Cancer= =20 treatment for men: Possible sexual side effects=20
Mouth=20 sores: Cancer-related causes and how to cope=20
PICC line:=20 How is it used for chemotherapy?=20
Opiate= =20 addiction and cancer therapy: Is it a concern?=20
EGFR = inhibitor=20 cancer therapy: What are the side effects?=20
Low=20 blood cell counts: Side effect of cancer treatment=20
Thalidomide= :=20 Research advances in cancer and other conditions=20
Ch= emotherapy=20 and sex: Is sexual activity OK during treatment?=20
Adjuva= nt=20 therapy: Treatment to keep cancer from returning=20
Cancer = treatment=20 myths: Any truth to these common beliefs?=20
Podcast:=20 Chemotherapy side effects =E2=80=94 What to expect=20
Podcas= t:=20 Watchful waiting and cancer therapy=20
Cancer= =20 treatment for women: Possible sexual side effects=20
Cancer= =20 treatment decisions: 5 steps to help you decide=20
Eating = during=20 cancer treatment: Tips to make food tastier=20
Cancer=20 fatigue: Why it occurs and how to cope=20
Chemotherapy=20 side effects: A cause of heart disease?=20
Mon= oclonal=20 antibody drugs for cancer treatment: How they work=20
Chemothera= py=20
Magic=20 mouthwash: Effective in treating chemotherapy mouth sores?=20
P= odcast:=20 Adjuvant chemotherapy: When is it used?=20
Ginge= r for=20 chemotherapy-induced nausea: Does it work?=20
Managing chemotherapy side effects=20
Compa= ssionate=20 use of experimental drugs: Who qualifies?=20
Radia= tion=20 therapy=20
Chemotherapy = and hair loss: What to expect during treatment=20
St= em cell=20 transplant=20
Gene=20 therapy=20
Chemotherapy=20 nausea and vomiting: Prevention is best defense=20
Palliat= ive=20 care: Easing the course of serious illness=20
Brachythe= rapy=20
Related=20 Links=20
Living=20 with cancer blog=20
Chemo=20 brain
Related Guides
Children=20
Parent

MY01327

June 10, 2010

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