From: Subject: Daily Herald | An alternative treatment for diabetic neuropathy Date: Thu, 20 May 2010 15:29:56 -0500 MIME-Version: 1.0 Content-Type: multipart/related; type="text/html"; boundary="----=_NextPart_000_0000_01CAF831.4D186210" X-MimeOLE: Produced By Microsoft MimeOLE V6.00.2900.5579 This is a multi-part message in MIME format. ------=_NextPart_000_0000_01CAF831.4D186210 Content-Type: text/html; charset="iso-8859-1" Content-Transfer-Encoding: quoted-printable Content-Location: http://www.dailyherald.com/story/print/?id=380773 Daily Herald | An alternative treatment for diabetic = neuropathy
3D"Daily
An alternative treatment for diabetic = neuropathy
By Dr. Patrick Massey | Columnist
Published:=20 5/17/2010 12:17 AM

Imagine having a constant burning feeling in your hands = and feet=20 with an associated feeling of numbness. You cannot do the simplest of = activities=20 like walking or shaking hands without pain and, over time, these = symptoms only=20 get worse. This is a medical condition called neuropathy. It affects 60 = percent=20 to 70 percent of diabetics and traditional medical therapy, quite = frankly, is=20 limited. Fortunately, recent medical research may have an answer and it = is alpha=20 lipoic acid. In diabetics, neuropathy may occur when the small blood = vessels=20 that feed the nerves are damaged by chronically elevated blood sugar = levels. All=20 types of nerves are affected, including those associated with pain, = sensation=20 and muscle function. The decreased blood supply causes the nerves to = misfire,=20 resulting in a feeling of pain, burning and numbness. Traditional = medical=20 therapies include the use of specific anti-seizure medications and=20 antidepressants. In addition, topical pain medications and stimulating = blood=20 flow in the tissues with infrared heat are commonly used. Unfortunately, = none of=20 these therapies can boast genuine success. The dietary supplement alpha = lipoic=20 acid may be a real addition to the medical options.

Alpha lipoic acid is a compound that is essential for = human life.=20 One of its functions is as an antioxidant. It also regenerates other=20 antioxidants like vitamin C and vitamin E. It was first used as a = therapeutic=20 agent in the mid-1950s by Franz Rausch M.D., who used it to bring = patients out=20 of comas related to liver failure. Since that time, alpha lipoic acid = has been=20 shown to be beneficial for many diseases including diabetic neuropathy, = liver=20 disease, improving memory and cognition, accelerating wound healing, = preventing=20 migraines and even preventing cell damage due to various types of = poisoning. As=20 far as memory and cognition, I have several Alzheimer's disease patients = who=20 have improved with alpha lipoic acid therapy.

Recently, a report published in the Netherlands Journal = of=20 Medicine summarized years of research on alpha lipoic acid and diabetic=20 neuropathy. The researchers did a systematic review of all the = publications and=20 clinical trials with alpha lipoic acid and diabetic neuropathy. This = type of=20 data collection is powerful because it combines the results of many = studies.=20 What they found was that alpha lipoic acid could reduce the symptoms of = diabetic=20 neuropathy by 50 percent. Although taking ALA by mouth was beneficial, = weekly=20 intravenous infusions of alpha lipoic acid significantly improved the = pain=20 associated with diabetic neuropathy.

Alpha lipoic acid is present in most foods but in very = small=20 amounts. In early alpha lipoic acid research, it took 10 tons of liver = to=20 isolate only 30 mg of alpha lipoic acid. Today, alpha lipoic acid is = chemically=20 synthesized and health benefits are associated with the concentrations = found in=20 specific dietary supplements (200 mg to 600mg).

Generally, alpha lipoic acid is safe. Side effects = include stomach=20 upset and at high doses, alpha lipoic acid may lower blood sugar. = Head-to-head=20 clinical trials with alpha lipoic acid and current medications for = diabetic=20 neuropathy have not been done, so it is difficult to compare overall=20 effectiveness. However, for those with diabetic neuropathy, alpha lipoic = acid=20 may be a real option.

=95Patrick B. Massey, M.D., Ph.D is medical director for = complementary and alternative medicine for the Alexian Brothers Hospital = Network.

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BORDER-TOP: #cccccc 1px solid; = PADDING-LEFT: 8px; PADDING-BOTTOM: 8px; PADDING-TOP: 8px; = BACKGROUND-COLOR: #ededed; TEXT-ALIGN: center } .leaderboardStory IMG { DISPLAY: block } .storySubNavBar { BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; = BORDER-LEFT-WIDTH: 0px; BACKGROUND: url(/images/site/subnav_bkg.gif) = repeat-x; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0px; = WIDTH: 980px; PADDING-TOP: 4px; HEIGHT: 29px; BORDER-RIGHT-WIDTH: 0px } .communityDropBox { PADDING-RIGHT: 0px; PADDING-LEFT: 0px; FONT-WEIGHT: bold; FONT-SIZE: = 9px; BACKGROUND: url(/images/site/com_drop_bkg_sty.gif) no-repeat; = FLOAT: right; PADDING-BOTTOM: 0px; MARGIN: 0px; TEXT-TRANSFORM: = uppercase; WIDTH: 235px; COLOR: #776b46; PADDING-TOP: 2px; FONT-FAMILY: = verdana; HEIGHT: 23px; TEXT-ALIGN: center } .storyColumnOne { BORDER-RIGHT: #dedede 1px solid; PADDING-RIGHT: 8px; DISPLAY: inline; = PADDING-LEFT: 0px; FLOAT: left; PADDING-BOTTOM: 8px; MARGIN: 0px; WIDTH: = 160px; PADDING-TOP: 8px } .storyColumnTwo { DISPLAY: inline; BACKGROUND: #ffffff; FLOAT: left; MARGIN: 8px; = OVERFLOW: hidden; WIDTH: 551px } DIV#centerStory { PADDING-RIGHT: 5px; PADDING-LEFT: 5px; BACKGROUND: = url(/images/site/center_bkg_story.gif) #ffffff repeat-y; PADDING-BOTTOM: = 0px; MARGIN: 0px auto; WIDTH: 980px; PADDING-TOP: 0px; POSITION: = relative; TEXT-ALIGN: left } .storyHeadline { CLEAR: both; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; FONT-WEIGHT: bold; = FONT-SIZE: 28px; PADDING-BOTTOM: 10px; PADDING-TOP: 0px; FONT-FAMILY: = "Times New Roman", Times, serif } .storySubHead { PADDING-RIGHT: 0px; PADDING-LEFT: 0px; FONT-WEIGHT: bold; FONT-SIZE: = 18px; PADDING-BOTTOM: 10px; COLOR: #797979; PADDING-TOP: 0px } .storyByline { PADDING-RIGHT: 0px; BORDER-TOP: #dddddd 1px dotted; PADDING-LEFT: 0px; = FONT-WEIGHT: 700; FONT-SIZE: 11px; BACKGROUND: #fefefe; PADDING-BOTTOM: = 4px; MARGIN: 0px; COLOR: #2e556c; PADDING-TOP: 4px; FONT-FAMILY: Arial } .storyByline2 { FONT-WEIGHT: 700; 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