December 2013

Is α-Synuclein Rising to the Surface as a Diagnostic Biomarker for Parkinson’s Disease?

The long held hope that a remedy will be discovered to halt the progress of Parkinson disease (PD) will require the identification of early, accurate, and accessible biomarkers. Editors write that if neuronal pathology leading to PD was shown to involve peripheral nerves and be present in a more safely accessible tissue, the ability to …

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α-Synuclein in Cutaneous Autonomic Nerves

This goal of this study was to develop cutaneous biomarkers for PD. Twenty patients with distal sensory and autonomic neuropathy underwent examinations, autonomic testing, and skin biopsies to measure α-Synuclein density within the epidermis, and nerve fibers that stimulate the sweat glands (sudomotor) and ‘move the hair’ – gooseflesh (pilomotor). READ MORE Source: Neurology

Neuropathic Pain: A Pathway for Care

Developed by the British Pain Society, this article highlights the creation of the Map of Medicine care pathway for the management of neuropathic pain. Focusing on treatment by non-specialists, this pathway is based on new evidence, consensus, and the interests of the service users.  READ MORE Source: British Journal of Anaesthesia