Inflammation associated with chronic pain states is deleterious to health and often debilitating for the patient. It has been hypothesized that pain of inflammatory origin may evolve into a condition that resembles neuropathic pain. This review by researchers from the Department of Neuroscience, Physiology and Pharmacology, University College London considers the therapeutic potential for sodium …
Dr. Xianglan Chang, Vanderbilt University School of Medicine, has just published results of a recent study indicating that Chinese men who practice Tai Chi were less likely to die over a five-year period than men who didn’t exercise at all. READ MORE Source: Denver Post
A comprehensive and systematic review of published literature for the treatment of diabetic peripheral neuropathy (DPN) from 1965 through 2012 has been completed at the Brody School of Medicine at East Carolina University and the East Carolina Diabetes and Obesity Institute. Their review showed that neuropathic pain is difficult to diagnose and treat and patients rarely experience …
Pharmacologic Management of Diabetic Peripheral Neuropathic Pain Read More »
Dr. Roy Freeman, Beth Israel Deaconess Medical Center, received funding from the NIH to pursue the review of specific drugs, newly approved or in development, to treat neuropathic pain in patients with diabetes. With a variety of drugs under review, the research focused on the mechanisms of action, preclinical supporting data, and adverse effects of …
New and Developing Drugs for the Treatment of Neuropathic Pain in Diabetes Read More »
The goal of this study was to assess the efficacy of oral medications on chronic peripheral neuropathy since studies typically report of short-duration outcomes and fail to account for medication tolerability. Seventeen studies were compared and results found that pregabalin and duloxetine had the highest beneficial effects for chronic neuropathic pain. READ MORE Source: Pain Medicine
Dr. Aaron Vinik, MD, PhD, Professor of Medicine and Director of Research at Eastern Virginia Medical School, and his team have developed an FDA-approved device which measures sweat glands to detect levels of peripheral neuropathy in patients with diabetes. READ MORE Source: Healio/Endocrine today
Duloxetine (ie, Cymbalta, and others) and pregabalin (ie, Lyrica) are used in the first line of treatment for diabetic peripheral neuropathy but have been shown to provide any relief in only about 40% of the patients. This study was focused on whether a combination therapy of duloxetine and pregabilin at standard doses may provide better pain …
Duloxetine and Pregabalin: High-dose monotherapy or their combination? Read More »
Researchers in Endocrinology at the university of Tor Vergata, Rome, published a review of available literature dealing with the similarities and differences between painful and painless DPN to try and determine if whether they are the same disease. Some people develop an ‘insensate’ variety of DPN while others experience distressing pain. READ MORE Source: Curr Diab Rep
A team of researchers at Queensland, School of Medicine, reviewed 24 studies to determine if nutraceuticals (i.e., vitamin E, acetyl-L-carnitine, glutamine, glutathione, alpha lipoic acid, magnesium, and others) are effective in reducing the peripheral neuropathy side effect in patients who have received chemotherapy treatments. The studies were mixed and currently no agent has shown solid …
Herb Fine is 92 years young. A veteran and retired lawyer, Herb has always had a passion to learn and to live life to the very fullest. He practiced law and worked in the courts of New York City for many years. Even at 81, he attended classes at the Florida Atlantic University Division for …
