Research

To achieve our Mission, the Foundation funds some of the most brilliant minds in neuroscience. Having recognized that no one laboratory has the compass to tackle the complex challenges of peripheral neuropathy, the Foundation organized a collaborative approach that will allow researchers to achieve a high level of trust, openness and collaborative interaction marked by dynamic, interactive and intellectual and scientific relationships between them. Collaborative efforts will foster the exchange of new information and cutting edge technologies with academic and industry researchers alike. We hope to increase the movement of new treatments into the clinic. Ultimately, the more that is known about the function and dysfunction of the nervous system, the more individuals can be helped to have a better future.

 

 

Research Studies Currently Recruiting Participants

 

Become an active participant in the search for more effective treatments and maybe even a cure by participating in one of the studies shared here:

 

Patient Assisted Intervention for Neuropathy:  Comparison of Treatment in Real Life Situations (PAIN-CONTRoLS)

A common cause of neuropathy is diabetes, but in about 25 to 50% of the population no cause is found.  This group is often referred to as cryptogenic sensory polyneuropathy (CSPN).  This study looks at four different drugs in patients with CSPN and plan to determine which drug is most effective: nortriptyline, duloxetine, pregabalin, or mexiletine.  The study is funded through PCORI: Patient-Centered Outcomes Research Institute whose research is "designed to improve patient care and outcomes through patient-centered comparative clinical effectiveness research."  Click here for locations!

 

 

Accelerated Research Therapy

Researchers at the University of South Florida College of Nursing are seeking volunteers to be a research study of Accelerated Resolution Therapy, for treatment of moderate to severe neuropathic pain.  Refer to study Pro00020802

 

The purpose of this study is to:

1)  Evaluate the effects of Accelerated Resolution Therapy (ART), a type of psychotherapy that can be delivered in just 1-5 sessions, over a 1-2 week time period, without medication, on pain severity and interference in participants with moderate to severe neuropathic pain.

 

2)  Evaluate the effects of ART on other healthy conditions, including depressive symptoms, anxiety, sleep quality, and quality of life in participants with moderate to severe neuropathic pain.

 

You can take part in this study if you meet the following criteria:

  • History of neuropathic pain for 3 months or more
  • Average pain over the last week of 6 or higher rated on a 0 to 10 scale
  • Age 21 or older
  • Able to read, write, and comprehend English
  • Under the care of a neurologist, primary care provider, or pain management specialist

 

You will not be eligible to take part in the study if you have had surgery, an invasive procedure, or major physical trauma within last 6 weeks, or have an implanted pain device (nerve stimulator, pain pump, etc.), have severe depressive symptoms or cognitive impairment.

 

The time commitment on your part will be 5-6 hours in total.  One to one and half hours of this would be spent filling out questionnaires and the rest of the time would be spent getting ART therapy.  From 1-5 sessions of ART therapy will be necessary.  The time you spend in ART therapy will depend on how you respond to it.

 

Potential benefits from being in the study include reductions in pain and possible improvement in quality of life as a result of having less pain.

 

You will not receive any monetary compensation for taking part in this study.

 

If you are interested in being in this study please contact the Principle Investigator Cindy Tofthagen at (813) 396-9441 or by email at ctofthag@health.usf.edu. (Recruiting through January 2016)

 

 

Acupuncture for Chemotherapy Induced Peripheral Neuropathy

Researchers at the University of South Florida College of Nursing are seeking 100 people to participate in a research study of acupuncture fro neuropathy caused by chemotherapy.  Refer to study Pro00021235.

 

If you have numbness, tingling, or discomfort in your hands or feet since getting chemotherapy, you may be eligible to receive acupuncture at no charge as part of this study.

 

If you are interested in being in this study please contact the Principle Investigator Cindy Tofthagen at (813) 396-9441 or by email at ctofthag@health.usf.edu. (Recruiting through June 2016)