November 2013

Neuropathic Pain Therapy: From Bench to Bedside

Most clinically available treatments for neuropathic pain, are borrowed from other therapeutic areas (antidepressants, antiepileptics) or involve older therapy (opiods). Patients often receive only partial pain relief. Dr. Miroslav ‘Misha’ Backonja, Department of Neurology, University of Wisconsin, conducted a study to determine if a combination of therapeutic agents is necessary to achieve and maintain satisfactory …

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Placebo Analgesia: Psychological and Neurobiological Mechanisms

In this review, we bring together three perspectives of placebo research including psychological mechanisms, neurobiological pathways and molecular substrates of placebo analgesia and their contribution to active pain medications. The emphasis is particularly on recent studies illuminating mechanisms underlying individual differences in placebo responsiveness.  READ MORE Source: NIH/National Institutes of Health