HIV Neuropathy

Key Data from FPN Patient Registry Highlighted in Top Medical Journal

In January 2019, a study was published by the Journal of the Peripheral Nervous System on the design and characteristics of patient data collected from the Peripheral Neuropathy Research Registry (PNRR). This is the first ever overall study performed on this Patient Registry and one that truly highlights the importance of this dataset for current …

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Study Reports Peripheral Neuropathy is Associated with Mitochondrial Dysfunction

A new study led by researchers at McGill University in Canada recently revealed that peripheral neuropathy is associated with a mitochondrial dysfunction and a bioenergetic impairment. Mitochondria are small cellular organelles in the body responsible for the production of energy through the process of respiration. Mitochondria dysfunction can impair the cellular energy metabolism, affecting several …

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HIV Sensory Neuropathy

Peripheral neuropathy presents clinically in 30–60% of people living with human immunodeficiency virus (HIV), and nearly all AIDS patients have an evidence of peripheral neuropathy at autopsy. HIV-associated sensory neuropathy (HIV-SN) is one of the most common forms of peripheral neuropathy. It has been found that 57% of HIV-infected individuals have distal symmetrical SN and …

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Pfizer Stops Phase 3 Trial of Lyrica Capsules CV in Neuropathic Pain Associated with HIV Neuropathy

Pfizer announced that it has stopped a Phase 3 clinical trail of Lyrica for patients with HIV neuropathy based on an interim analysis of the results. “The results of this study show the complexities of studying pain, particularly in a difficult-to-treat condition such as neuropathic pain associated with HIV neuropathy for which there are no …

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Spinal Cord Stimulation Effective for HIV Neuropathy

At the 6th World Congress of the World Institute of Pain in Miami Beach this month, Dr. Kenneth Candido presented a poster on the success of implanting a permanent device that delivers constant spinal cord stimulation to offer pain relief to patients with HIV-related polyneuropathy. Dr. Candido is chair and professor in the Department of …

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NeurogesX Submits Supplemental new Drug Application for Qutenza (R) 8% Patch for HIV-Associated Peripheral Neuropathy

Biopharmaceutical company, NeurogesX, announced it submitted a supplemental new drug to the US FDA seeking to expand the label to include an application for the management of pain due to HIV-associated neuropathy. FDA Priority Review status is given to drug candidates that offer major advances in treatment and accelerated the standard review time. HIV-PN is …

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High Triglycerides Increase Risk of Neuropathy for Patients with HIV

In a study conducted by Dr. Sugato Banerjee of the HIV Neurobehavioral Research Center in San Diego and his colleagues a potential connection has been found between elevated lipid levels and neuropathy in people receiving antiretroviral treatments. Managing the elevated triglyceride levels may reduce the risk of developing this debilitating nerve condition.  READ MORE Source: …

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Capsaicin Patch Eases HIV Neuropathy Pain

In a report presented at the American Academy of Pain Medicine, Dr. Stephen J. Brown, states that difficult to treat HIV-associated neuropathic pain appears to be eased for at least three months with a one-time, 30-minute application of an 8% capsaicin patch. Brown said, “More than half of people with HIV-infection develop neuropathy, and about …

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HIV Peripheral Neuropathy: 2010 Archive

Pregabalin for Painful HIV Neuropathy June 2010: Dr. David Simpson and a team of researchers have been evaluating effective treatments for painful HIV neuropathy. Their current findings, ‘A randomized, double-blind, placebo-controlled trial’ have been published in the Neurology journal. Learn more about Pregabalin for Painful HIV Neuropathy Source: Dr. Simpson, Mount Sinai Learn more about Dr. …

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