Other PN News

FDA Drug Safety Communication: FDA requires label changes to warn of risk for possibly permanent nerve damage from antibacterial fluoroquinolone drugs taken by mouth or by injection

The U.S. Food and Drug Administration (FDA) has required the drug labels and medication guides for all fluoroquinolone antibacterial drugs be updated to better describe the serious side effect of peripheral neuropathy. This serious nerve damage potentially caused by fluoroquinolones may occur soon after these drugs are taken and may be permanent. The risk of …

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Lyme Disease Under-reported, Incidence Still on the Rise

Lyme disease, one cause of peripheral neuropathy, continues to be the most commonly reported vector-borne illness in the US. It was the 7th most common nationally notifiable disease in 2012 with many cases that go unreported. Three complementary studies are currently being conducted by the CDC to better quantify how many people are actually diagnoed with …

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Is α-Synuclein Rising to the Surface as a Diagnostic Biomarker for Parkinson’s Disease?

The long held hope that a remedy will be discovered to halt the progress of Parkinson disease (PD) will require the identification of early, accurate, and accessible biomarkers. Editors write that if neuronal pathology leading to PD was shown to involve peripheral nerves and be present in a more safely accessible tissue, the ability to …

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α-Synuclein in Cutaneous Autonomic Nerves

This goal of this study was to develop cutaneous biomarkers for PD. Twenty patients with distal sensory and autonomic neuropathy underwent examinations, autonomic testing, and skin biopsies to measure α-Synuclein density within the epidermis, and nerve fibers that stimulate the sweat glands (sudomotor) and ‘move the hair’ – gooseflesh (pilomotor). READ MORE Source: Neurology

FDA Requires Stronger Peripheral Neuropathy Warning for Quinolones

The Food and Drug Administration is requiring a stronger warning about the potential for peripheral neuropathy with fluoroquinolone antibiotics that are taken orally or by injection. The warning does not apply to topical formulations, which have not been associated with neuropathy. Drug labels and patient medication guides must be updated, said the agency.  READ MORE …

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Blocking Neuropathic Pain Before it Starts

Researchers at Boston Children’s Hospital and the Massachusetts Institute of Technology have found a way to delay neuropathic pain in animals. Using tiny spheres filled with a powerful anesthetic may provide a way to provide relief, blocking the pain before it starts. READ MORE Source: PRNewsWire