Diabetic Peripheral Neuropathy

A new UK study, published in the American Journal of Respiratory and Critical Care Medicine shows that obstructive sleep apnea (OSA) is independently linked to diabetic peripheral neuropathy (DPN) in patients with Type 2 diabetes. In their observational, cross-sectional study, Dr. Abd Tahrani, clinical lecturer in diabetes and endocrinology at the UK’s University of Birmingham, and his team found that OSA …

Obstructive Sleep Apnea is Associated with Diabetic Peripheral Neuropathy Read More »

Researchers at Wan Fang Hospital in Taipei, Taiwan, have conducted a study to determine if early axonal dysfunction can be detected prior to the onset of diabetic peripheral neuropathy. Dr. Jia-Ying Sung and colleagues found that patients with type 2 diabetes but no clinical symptoms of neuropathy displayed changes in excitability parameters of the nerves …

Early Axonal Dysfunction Precedes Diabetic Neuropathy Read More »

Research published in Nature Medicine reveals key information around one of the most distressing side effects of diabetes. This study offers vital new insights into how abnormal glucose metabolism produces heightened pain in diabetics. Further research is being undertaken to develop new treatments.  READ MORE Source: Science Daily

Researchers from Yale and the West Haven Veterans Affairs Medical Center have published findings in the Journal of Neuroscience describing how changes in the structure of dendritic spines are associated with pain in laboratory rats with diabetes. Dendritic spines are microscopic projections on the receiving branches of nerve calls. This study “reveals that these dendritic …

Yale Team Discovers Unexpected Source of Diabetic Neuropathic Pain Read More »

The US FDA has agreed to resume clinical trials with anti-nerve growth (NGF) drugs despite cases of side effects stating the risk-benefit profile indicated a role for their ongoing development. The drugs are being developed for the treatment of a variety of chronic painful conditions, including diabetic peripheral neuropathy. READ MORE Source: Medscape

The results of a 13-week study by Avanir Pharmaceuticals, published in the journal Pain Medicine, show efficacy and safety of AVP-923 for treatment of diabetic neuropathic pain. Currently also in study for multiple sclerosis, the combination of Dextromethorphan and Quinidine (AVP-923) showed its effectiveness in treating diabetic neuropathic pain, particularly a reduction in leg pain. READ …

Publication of Phase III Study Shows Positive Results for Diabetic Neuropathic Pain Read More »