Duloxetine and Pregabalin: High-dose monotherapy or their combination?

Duloxetine (ie, Cymbalta, and others) and pregabalin (ie, Lyrica) are used in the first line of treatment for diabetic peripheral neuropathy but have been shown to provide any relief in only about 40% of the patients. This study was focused on whether a combination therapy of duloxetine and pregabilin at standard doses may provide better pain relief and tolerability than using either drug alone at maximum doses.  READ MORE

Source: PAIN