Opioids for Neuropathic Pain
A study was recently published in the Cochrane Library to reassess the efficacy and safety of opioid agonists for the treatment of neuropathic pain. READ MORE Source: Cochrane Library
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Neuropathic Pain
Combination Pharmacotherapy for Management of Chronic Pain: From Bench to Bedside
Research published by Queens University recently indicates that combination therapy remains an important beneficial strategy to treating chronic pain. Though different classes of drugs are being used to treat chronic pain, current medications are limited by incomplete efficacy and dose-limiting side effects. READ MORE Source: The Lancet
UB Study to Identify Molecular Process Leading to Peripheral Pain
A faculty member in the UB medical school has received a $1.2 million federal grant to study the gating mechanism of a temperature-sensitive ion channel protein found abundantly in peripheral nerve endings. The research by Feng Qin, associate professor of physiology and biophysics, on the vanilloid receptor TRPV1 could lead to new drugs that target …
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Equivalency of Tricyclic Antidepressants in Open-Label Neuropathic Pain Study
Researchers from the Department of Clinical Neurosciences, the Hotchkiss Brain Institute, and the University of Calgary, just published results of a study to compare adverse effects, tolerability and efficacy of the tricyclic antidepressants (TCAs) amitriptyline and nortriptyline in management of neuropathic pain due to peripheral neuropathy (PN). Their results show that amitriptyline and nortriptyline are …
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Voltage Gated Sodium and Calcium Channel Blockers for the Treatment of Chronic Inflammatory Pain
Inflammation associated with chronic pain states is deleterious to health and often debilitating for the patient. It has been hypothesized that pain of inflammatory origin may evolve into a condition that resembles neuropathic pain. This review by researchers from the Department of Neuroscience, Physiology and Pharmacology, University College London considers the therapeutic potential for sodium …
Comparative Efficacy of Oral Pharmaceuticals for the Treatment of Chronic Peripheral Neuropathic Pain
The goal of this study was to assess the efficacy of oral medications on chronic peripheral neuropathy since studies typically report of short-duration outcomes and fail to account for medication tolerability. Seventeen studies were compared and results found that pregabalin and duloxetine had the highest beneficial effects for chronic neuropathic pain. READ MORE Source: Pain Medicine
Living with Pain
Reports show that 50 percent of chronic pain patients consider suicide to escape their physical pain. Neurology Now has just published an uplifting article to help people make the choice to ‘choose life.’Â READ MORE Source:Â NeurologyNow
Research Findings Could Lead to Improved Treatment for Neuropathic Pain
Led by the University of California, San Diego School of Medicine, international researchers say a key protein in Schwann cells performs a critical role in regulating the recovery of peripheral nerves after injury. This discovery could have implications for improving the treatment of neuropathic pain which affects over 100 million Americans. READ MORE Source: NewsMedical
A Randomized, Single-Blind, Controlled, Parallel Assignment Study of Exercise Versus Education as Adjuvant in the Treatment of Neuropathic Pain
Researchers in Canada, published results of a clinical study that was used to evaluate the impact of balanced exercise therapy for maintenance of pain relief versus education. Out of the 78 patients screened, 54 participated in the study. READ MORE Source: ClinicalPain
Neuropathic Pain: 2009 Archive
The Sea Provides A New Hope of Relief A compound initially isolated from a soft coral (Capnella imbricata) collected at Green Island off Taiwan, could lead scientists to develop a new set of treatments for neuropathic pain – chronic pain that sometimes follows damage to the nervous system. Currently this form of pain is very …