EpiCept Corp. has received formal scientific advice from the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) that are aligned with the recent guidance given by the U.S. FDA regarding the development of AmiKet, for the treatment of CIPN. EpiCept has reported significant postiive results in the treatment of …
Scientists at the University of CA San Francisco have published new findings in Neuron regarding the use of stem cells to treat chronic nerve pain. Led by Dr. Allan Basbaum, the teams believes stem cells may possibly cure some types of neuropathic conditions. READ MORE from EmaxHelath or READ MORE from Neuron. Source: EmaxHealth; Neuron
Pfizer announced that it has stopped a Phase 3 clinical trail of Lyrica for patients with HIV neuropathy based on an interim analysis of the results. “The results of this study show the complexities of studying pain, particularly in a difficult-to-treat condition such as neuropathic pain associated with HIV neuropathy for which there are no …
Researchers at Wan Fang Hospital in Taipei, Taiwan, have conducted a study to determine if early axonal dysfunction can be detected prior to the onset of diabetic peripheral neuropathy. Dr. Jia-Ying Sung and colleagues found that patients with type 2 diabetes but no clinical symptoms of neuropathy displayed changes in excitability parameters of the nerves …
Early Axonal Dysfunction Precedes Diabetic Neuropathy Read More »
Pfizer announced that a Phase 3 randomized withdrawal design study for Lyrica in patients with inadequately treated painful diabetic peripheral neuropathy did not meet its primary efficacy endpoint. READ MORE Source: Marketwatch
Research published in Nature Medicine reveals key information around one of the most distressing side effects of diabetes. This study offers vital new insights into how abnormal glucose metabolism produces heightened pain in diabetics. Further research is being undertaken to develop new treatments. READ MORE Source: Science Daily
Researchers from Yale and the West Haven Veterans Affairs Medical Center have published findings in the Journal of Neuroscience describing how changes in the structure of dendritic spines are associated with pain in laboratory rats with diabetes. Dendritic spines are microscopic projections on the receiving branches of nerve calls. This study “reveals that these dendritic …
Yale Team Discovers Unexpected Source of Diabetic Neuropathic Pain Read More »
Janssen Pharmaceuticals, Inc. presented results at the 31st Annual Scientific Meeting of the American Pain Society suggesting these extended-release tablets were significantly more effective than placebo in providing pain management among adults with chronic moderate to severe, painful diabetic peripheral neuropathy. “Painful DPN is a common and burdensome complication of diabetes, and controlling pain in …
Phase 3 Data Show NUCYNTA® ER Extended-Release Tablets Provide Pain Relief Management Read More »
Dr. Richard Ostfeld, a disease ecologist at the Cary Institute of Ecosystem Studies in Millbrook, NY, says the northeastern US should prepare for a surge in Lyme disease this year. May through July will be particularly dangerous according to Dr. Ostfeld. Lyme disease carries significant side effects, including peripheral neuropathy and other neurological conditions. READ …
Lyme Disease Surge Predicted for Northwestern US Read More »
Professor John Wood at UCL Wofson Institute for Biomedical Research has new findings the could help the development of analgesic drugs to treat nerve-related damage. Published in the journal Nature Communication his research has identified specific neurons in mice that are important for transmitting particular types of pain and that the transmission of neuropathic pain is dependent …
