Diabetic Peripheral Neuropathy

lab researcher working with lab equipment

New Study Shows Tapentadol Extended Release May Significantly Reduce Average Pain for Diabetic Peripheral Neuropathy

With more than 26 million people in the US living with diabetes, as reported by the Centers for Disease Control, approximately 60-70% of them will develop nerve damage called neuropathy at some point. New research has been published indicating that patients suffering with diabetic peripheral neuropathy (DPN) may experience a significant improvement in their pain …

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A Skin Cream for Peripheral Neuropathy? Small Molecule May go a Long Way

About half of people with diabetes develop peripheral neuropathy. While there are some treatments to reduce pain, there’s nothing that restores sensation. Gabriel Corfas, PhD, of the F.M. Kirby Neurobiology Center at Boston Children’s Hospital, wondered if replenishing a growth factor called GDNF (short for glial-derived neurotrophic factor) could improve sensory neurons’ health and function. …

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Managing Diabetes with Exercise: 6 Tips for Nerve Pain

If you have diabetic nerve pain in your feet, legs, arms, or hands, consider this: research published in The Journal of Diabetes Complications showed significant benefits of exercise in controlling peripheral neuropathy. The study showed that for people who took a brisk, one-hour walk on a treadmill four times a week, exercise slowed how quickly their nerve …

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Peripheral Neuropathy Common in Youth with Type 2 Diabetes

Dr. Eva Feldman, MD, PhD, the Russell N. DeJong Professor of Neurology and director of the A. Alfred Taubman Medical Research Institute at the University of Michigan reports that around a quarter of young people with type 2 diabetes also have diabetic peripheral neuropathy, a new pilot study indicates. The prevalence of diabetic peripheral neuropathy …

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Tibial Nerve Decompression Failed to Improve Painful Diabetic Polyneuropathy

It has been hypothesized that the development of diabetic polyneuropathy (DPN) is due to swelling of the nerve, as well as thickening and stiffening of the surrounding ligaments, causing chronic compression of nerves. Researchers examined the effect of surgical decompression of the tibial nerve on the mean cross sectional area (CSA). Results indicated there was …

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ADA's 2014 Standards of Care Emphasizes Individualized Treatment

The ADA’s annually revised Standards of Medical Care in Diabetes was just released with an emphasis on individualized treatment of diabetes. Their position paper indicates that, “It is clear that optimal diabetes management requires an organized, systematic approach and involvement of a coordinated team of devoted healthcare professionals…”. The recommendations encourage clinicians to seek various …

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Pharmacologic Management of Diabetic Peripheral Neuropathic Pain

A comprehensive and systematic review of published literature for the treatment of diabetic peripheral neuropathy (DPN) from 1965 through 2012 has been completed at the Brody School of Medicine at East Carolina University and the East Carolina Diabetes and Obesity Institute. Their review showed that neuropathic pain is difficult to diagnose and treat and patients rarely experience …

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New and Developing Drugs for the Treatment of Neuropathic Pain in Diabetes

Dr. Roy Freeman, Beth Israel Deaconess Medical Center, received funding from the NIH to pursue the review of specific drugs, newly approved or in development, to treat neuropathic pain in patients with diabetes. With a variety of drugs under review, the research focused on the mechanisms of action, preclinical supporting data, and adverse effects of …

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